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Clinical study of 40Hz light stimulation combined with intermittent theta pulse transcranial magnetic stimulation for the treatment of chronic insomnia

Clinical study of 40Hz light stimulation combined with intermittent theta pulse transcranial magnetic stimulation for the treatment of chronic insomnia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107570
Enrollment
Unknown
Registered
2025-08-14
Start date
2025-08-15
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

insomnia

Interventions

40Hz light+iTBS group:40Hz light+iTBS intervention
sham 40Hz light+iTBS group:sham 40Hz light+iTBS intervention
40Hz light+ sham iTBS group:40Hz light+ sham iTBS intervention

Sponsors

Affiliated Kangning Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Meet the diagnostic criteria for chronic insomnia as stipulated in the International Classification of Diseases, Tenth Revision (ICD-10). 2.The Pittsburgh sleep quality index (PSQI) score was greater than 5 points before treatment; 3. No concurrent mental disorders such as depression and anxiety, nor neurological diseases such as stroke, dementia, Parkinson's disease, and chronic pain; 4.Age: 18 to 65 years old, gender not limited. 5.Primary school education or above; 6.Patients voluntarily participated in this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1.History of physical illness, organic brain diseases and substance abuse; 2.Those who have had epileptic seizures before; 3.Those with metal objects such as pacemakers, stents, and inner ear hearing AIDS in their bodies; 4.Patients at risk of seizures, with previous craniocerebral diseases, head trauma, alcoholism, EEG abnormalities, MRI ev; 5.Pregnant or lactating women; 6.Check the experimenters who are uncooperative and unable to complete the task.

Design outcomes

Primary

MeasureTime frame
Clinical Scale Assessment;

Secondary

MeasureTime frame
Near infrared functional imaging;EEG change;Electromyographic changes;Behavioral tasks;nuclear magnetic;

Countries

China

Contacts

Public ContactQi Zhou

Affiliated Kangning Hospital of Ningbo University

993688007@qq.com+86 574 2630 2520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026