Diabetic nephropathy
Conditions
Interventions
Intervention group:ake 10 pills of Compound Danshen Dripping Pills each time, 3 times a day.
Control group:Conventional treatment
Sponsors
General Hospital of Central Theater Command of the Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-60 years, regardless of gender; (2) Clearly diagnosed with DKD according to the diagnostic criteria for diabetic kidney disease in the 2021 Chinese Clinical Practice Guidelines for Diabetic Kidney Disease; eGFR > 45 ml·min?¹·(1.73m²)?¹, urinary albumin-to-creatinine ratio > 30mg/g (stages G1-3aA2-3); glycosylated hemoglobin (HbA1c) is 7.0%-10.0%. (3) The study protocol was reviewed and approved by the Ethics Committee, and all patients signed written informed consent forms before participation.
Exclusion criteria
Exclusion criteria: (1) Type 1 diabetes or other special types of diabetes; (2) Pregnant, lactating women, or women planning to become pregnant; (3) Those taking Compound Danshen Dripping Pills or other Chinese patent medicines and Chinese herbal medicines; (4) Patients with other kidney diseases, or autoimmune diseases (rheumatism, asthma, etc.); (5) Patients with acute diabetic complications; (6) Patients with severe digestive system diseases who cannot tolerate drug treatment; (7) Patients with tumors, severe lesions of important organs such as heart, liver and kidney, coagulation dysfunction, large-area cerebral infarction, or those with language disorders or consciousness disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| N-cadherin;E-cadherin; | — |
Secondary
| Measure | Time frame |
|---|---|
| ROCK;MYPT1;Scr;UACR;UTP;eGFR;NAG;RBP;a1-MG;ß2-MG; | — |
Countries
China
Contacts
Public ContactDong Jing
General Hospital of Central Theater Command of the Chinese People's Liberation Army
Outcome results
None listed