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Development of a Precision Classification Model for Uric Acid Stones Based on Multimodal Parameters: A Multicenter Observational Study

Development of a Precision Classification Model for Uric Acid Stones Based on Multimodal Parameters: A Multicenter Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107525
Enrollment
Unknown
Registered
2025-08-13
Start date
2025-08-20
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urolithiasis includes renal calculi, ureteral calculi, bladder calculi, and urethral calculi.

Interventions

Gold Standard:Infrared spectroscopy for the analysis of urinary stones.
Index test:A precision classification model for uric acid stones based on multimodal parameters

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis of urinary tract stones is clearly established, including renal calculi, ureteral calculi, bladder calculi, and urethral calculi. 2. During the study period, patients underwent surgical treatment at participating medical centers, including ureteroscopic/retrograde intrarenal surgery (RIRS), percutaneous nephrolithotomy (PCNL), pyelolithotomy/ureterolithotomy, and transurethral cystolithotripsy. 3.The composition of urinary tract stones was analyzed postoperatively using infrared spectroscopy.

Exclusion criteria

Exclusion criteria: 1.To avoid heterogeneity caused by multiple stones (e.g., discrepancies between the target stone measured on CT and the stone analyzed for composition), patients with multiple or multifocal urolithiasis—including multiple renal stones or renal stones with concurrent ureteral stones—will be excluded. 2.Women who are pregnant or breastfeeding, and pediatric patients under 18 years of age.

Design outcomes

Primary

MeasureTime frame
Uric acid stones and non-uric acid stones;C-index;Receiver operating characteristic curve;AUC;

Countries

China

Contacts

Public ContactZhuo Jian

Shanghai General Hospital

002046zj@shgh.cn+86 21 63240090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026