Skin pigmentation
Conditions
Interventions
Control:the base formula of the experimental group's product. It is identical to the experimental group's product in all aspects except for the absence of tranexamic acid, and has a similar appearance
experimental group:a topical tranexamic acid preparation
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: astaring@163.com, you can contact them 6 months after the end of the trial 1. Volunteer to participate in this trial, sign the informed consent form, agree to use the product and conduct testing; 2. Age within the range of 20-60 years old, male or female; 3. Meet the diagnostic criteria for post-inflammatory pigmentation and melasma, and adopt the expert consensus on the prevention and treatment of post-inflammatory pigmentation (2024 edition ) and the Chinese expert consensus on the diagnosis and treatment of melasma (2021 edition).
Exclusion criteria
Exclusion criteria: 1. Failure to fill in the informed consent form; 2. Pregnant or pregnant or lactating; 3. Those who have taken tranexamic acid or topical tranexamic acid in the past month; 4. Those who take oral contraceptives or hormone replacement therapy; 5. For those who are allergic to known ingredients of the product and patients with severe allergies; 6. Has a severe or progressive disease that, in the judgment of the investigator, presents an inappropriate risk for the subject to participate in this clinical trial (i.e., cancer or cancer symptoms, immunocompromised, uncontrolled diabetes, epilepsy, severe cardiovascular and cerebrovascular disease) 7. Those with other pigmented, immune and infectious skin diseases; 8. Other topical drugs and oral drugs with freckle removal and whitening effects have been used in the 2 weeks before and during the trial; 9. Other conditions that the investigator deems unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma lesion area and severity index;Doctor's overall score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient assessment;evaluation of product satisfaction; | — |
Countries
China
Contacts
Public ContactLi Li
West China Hospital, Sichuan University
Outcome results
None listed