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A study on the efficacy and electroencephalogram spectrum characteristics of tACS in regulating sleep quality and improving mild cognitive impairment in the elderly

A study on the efficacy and electroencephalogram spectrum characteristics of tACS in regulating sleep quality and improving mild cognitive impairment in the elderly

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107503
Enrollment
Unknown
Registered
2025-08-13
Start date
2025-08-18
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

Experimental Group :tACS stimulation
Control Group:tACS sham stimulation

Sponsors

The Affiliated SuZhou Hospital of Nanjing University Medical School (Suzhou Municipal Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Aged between 60 and 75. 2) Meet the diagnostic criteria for MCI. 3) Meet the diagnostic criteria for MCI. 4) They had a Pittsburgh Sleep Quality Index (PSQI) score greater than 6 points before treatment. 5) No concurrent mental disorders such as depression and anxiety, nor neurological diseases such as stroke, dementia, Parkinson's disease and chronic pain. 6) Right-handed. 7) Be able to understand and cooperate, and be willing to participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Depressed patients with a score of =9 on the 15-item Geriatric Depression Scale (GDS-15). 2) Have taken any antipsychotic drugs within the past month. 3) Those with uncontrolled hypertension (systolic blood pressure >160 mmHg or diastolic blood pressure 11%). 5) Those unable to cooperate in completing the tACS programme due to motor function disorders caused by neurological diseases or severe organ diseases. 6) Those who are unable to complete the indicator assessment due to severe aphasia, visual and auditory impairments or illiteracy. 7) Those who are currently participating in other research trials that could influence the results of this study.

Design outcomes

Primary

MeasureTime frame
Subjective sleep quality;Overall cognitive function;

Secondary

MeasureTime frame
Overall memory level;Epworth Sleepiness Scale;EEG electroencephalogram spectrum;

Countries

China

Contacts

Public ContactTang Tong

The Affiliated SuZhou Hospital of Nanjing University Medical School (Suzhou Municipal Hospital)

15952168154@163.com+86 159 5216 8154

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026