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Efficacy and Safety of Cerebellar Transcranial Direct Current Stimulation for Post-Stroke Aphasia: A Randomized Controlled Trial

Efficacy and Safety of Cerebellar Transcranial Direct Current Stimulation for Post-Stroke Aphasia: A Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107492
Enrollment
Unknown
Registered
2025-08-12
Start date
2024-03-27
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke aphasia

Interventions

Trial group:Cathodal transcranial direct current stimulation (tDCS) of the cerebellum

Sponsors

Rehabilitation Medicine Center, Zhujiang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The participant voluntarily agrees to participate in the study and has signed the informed consent form; 2. Male or female, aged 18 to 80 years, right-handed; 3. Meets the diagnostic criteria for patients with aphasia following left-hemisphere stroke; 4. 3 to 12 months post-stroke; 5. Conscious and hemodynamically stable, able to cooperate with treatment and understand task execution.

Exclusion criteria

Exclusion criteria: 1. Presence of right cerebellar lesion; 2. Patients with intracranial metallic implants; 3. Sensitive scalp; 4. History of psychiatric disorders or other neurological diseases; 5. Presence of severe visual or auditory impairments; 6. Unwillingness to cooperate with the assessment.

Design outcomes

Primary

MeasureTime frame
Chinese Standard Aphasia Scale (CRRCAE);

Secondary

MeasureTime frame
brain activation and variations in FC using fNIRS;The change in fNIRS oxyhemoglobin concentration compared with the baseline value after 10 days of treatment;

Countries

China

Contacts

Public ContactQing Zeng

Rehabilitation Medicine Center, Zhujiang Hospital of Southern Medical University, No. 253, Industrial Avenue Zhong, Haizhu District, Guangzhou, Guangdong Province

zengqingyang203@126.com+86 159 8918 9468

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026