laryngopharyngeal reflux
Conditions
Interventions
Gold Standard:Positive laryngopharyngeal reflux group: Reflux Symptom Index > 13 points and/or Reflux Finding Score > 7 points
Negative control group: Reflux Symptom Index = 13 points and Reflux Finding Score = 7 points.
Index test:magnifying endoscopy with blue laser imaging
Sponsors
900th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force
Eligibility
Sex/Gender
All
Age
23 Years to 67 Years
Inclusion criteria
Inclusion criteria: Patients with laryngopharyngeal reflux symptoms, aged 18-70 years.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot tolerate endoscopy, or have other contraindications to endoscopy; 2. Patients with a history of pharyngeal or gastrointestinal surgery or trauma; 3. Patients with severe systemic diseases or mental illnesses; 4. Patients who do not follow medical instructions and have poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Laryngeal and pharyngeal manifestations under electronic chromoendoscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Results of dual-channel esophageal pH-impedance monitoring;Results of pepsin immunohistochemical staining in laryngopharyngeal biopsy tissues; | — |
Countries
China
Contacts
Public ContactRong Wang
900th Hospital of the Joint Logistic Support Force
Outcome results
None listed