Gynecological tumors, endometriosis, ovarian cysts and other gynecological diseases
Conditions
Interventions
Propofol group:Propofol target-controlled infusion
Remimazolam group:Remimazolam target-controlled infusion
Sponsors
Foshan Maternity & Child Healthcare Hospital,
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. 18–65 years old; 2. American Society of Anesthesiologists (ASA) physical status of I-II; 3. Patients undergoing elective gynecological laparoscopic surgery;
Exclusion criteria
Exclusion criteria: 1. Allergy to drugs used in the study; 2. severe heart and lung disease; 3. Mental and neurological disorders; 4. Uncontrolled stable hypertension, diabetes; 5. Patients who undergo gynecological laparoscopic surgery and switch to open surgery; 6. Severe organ dysfunction; 7. Pregnant and lactating female patients; 8. Alcoholics patients; 9. Patients with myasthenia gravis; 10. Patients with severe depression; 11. Schizophrenia patients;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time to emergence, defined as the interval from discontinuation of study drugs to eye opening upon verbal command; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time in PACU;Incidence of adverse events;Incidence of using intraoperative vasoactive agents Vasopressors, atropine, remifentanil and rescue medications;Emergence sedation and analgesic score;Time point for Modified Aldrete Score =9;Extubation time;Duration of anesthesia and surgery;Orientation recovery time; | — |
Countries
China
Contacts
Public ContactJunling Li
Foshan Maternity & Child Healthcare Hospital,
Outcome results
None listed