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The diagnostic and prognostic value of blood vitamin auto-fluorescence for early-stage acute intestinal ischemia

The diagnostic and prognostic value of blood vitamin auto-fluorescence for early-stage acute intestinal ischemia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107462
Enrollment
Unknown
Registered
2025-08-12
Start date
2024-07-25
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute intestinal ischemia

Interventions

Gold Standard:Definitive radiographic findings on CTA and/or postoperative pathological reports suggest ischemic necrosis of resected intestine.
Index test:Plasma riboflavin auto--fluorescence

Sponsors

The Second Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age>=18 years old; 2. Sudden acute abdominal pain, the scope and nature of abdominal pain are not limited; 3. Have one or more accompanying symptoms such as nausea and vomiting, diarrhea, blood in the stool, and cessation of exhaust and defecation; 4. I and my family members are informed and agree to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Age< 18 years old; 2. Pregnancy status; 3. Intestinal injury caused by endoscopic treatment, radiointerventional therapy or surgery within 1 week before admission; 4. Those who have developed multiple organ failure and are in critical condition at the time of admission; 5. Suffering from mental illness or poor compliance, unable to cooperate with this study; 6. I and/or my family members do not agree to participate in this study.

Design outcomes

Primary

MeasureTime frame
Intensity of plasma riboflavin auto-fluorescence ;Sensitivity;Specificity;Positive predictive value;Negative predictive value;

Secondary

MeasureTime frame
White blood cell count;C-reactive protein;Procalcitonin;Aspartate aminotransferase;Lactate dehydrogenase;Lactate;Creatine kinase;D-dimer;Intestinal fatty acid-bind protein;

Countries

China

Contacts

Public ContactDehai Wu

The Second Affiliated Hospital of Harbin Medical University

jumbohmuedu@163.com+86 151 0450 1496

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026