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Comparison of Anrikefon and Sufentanil on Postoperative Pain and Nausea-Vomiting in Patients Undergoing Laparoscopic Uterine Surgery

Comparison of Anrikefon and Sufentanil on Postoperative Pain and Nausea-Vomiting in Patients Undergoing Laparoscopic Uterine Surgery: a random, control,double-blinded and prospective clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107453
Enrollment
Unknown
Registered
2025-08-12
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea- vomiting and pain following laparoscopic uterine surgery

Interventions

Anrikefon group:Anrikefon Injection
Sufentanil group:Sufentanil injection

Sponsors

The First People's Hospital of Foshan
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Sign a dated informed consent form voluntarily; 2. Females aged 18 to 65 years old; 3. Patients scheduled for laparoscopic uterine surgery; 4. American Society of Anesthesiologists (ASA) Physical Status I to III; 5. Patient-controlled intravenous analgesia should be applied after the operation.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; 2. BMI >= 35 kg/m^2; 3. Allergic to drugs used in this study; 4. Preoperative coexistence of severe cardiovascular or cerebrovascular diseases; 5. Preoperative coexistence of severe respiratory system diseases; 6. Preoperative coexistence of severe liver disease; 7. Patients with preoperative renal dysfunction (serum creatinine exceeding 176 µmol/L); 8. Alcohol addiction history; 9. Long-term use of opioids or other analgesic; 10. Due to various reasons, they were unable to understand the application of PCIA or were unable to cooperate with the pain rating personnel.

Design outcomes

Primary

MeasureTime frame
the incidence of postoperative nausea and vomiting within 24h from the end of the surgery;

Secondary

MeasureTime frame
The NRS score for pain during 48 hours after the operation;

Countries

China

Contacts

Public ContactHanbing Wang

The First People's Hospital of Foshan

whbing@fsyyy.com+86 18038862186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026