Spinal metastases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 to 90 years with imaging-confirmed epidural spinal cord compression (ESCC) classified as high-grade or extreme high-grade on the 12-point scale were eligible for inclusion. Participants were required to exhibit at least one of the following progressive clinical manifestations: (A) worsening localized mechanical or radicular pain, (B) deteriorating sensory function, (C) motor impairment in the lower extremities, or (D) sphincter dysfunction. Additionally, candidates had to be surgically eligible with no contraindications and demonstrate willingness to adhere to follow-up protocols.
Exclusion criteria
Exclusion criteria: Patients were excluded if they had primary spinal malignancies (other than spinal myeloma), intramedullary metastases from spinal tumors, or prior surgical/radiotherapeutic intervention at the primary affected vertebral level. Additional exclusions comprised severe comorbidities, including cardiocerebrovascular diseases, respiratory disorders, active severe infections, significant hepatic/renal dysfunction, coagulopathies, or psychiatric conditions that contraindicated general anesthesia or surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative complication;Postoperative muscle loss;Postoperative functional outcome; | — |
Countries
China
Contacts
Chinese PLA General Hospital