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The Construction and Validation of an Intelligent Prognostic Prediction Platform for Postoperative Outcomes in MESCC Based on Multidimensional Clinical Data

The Construction and Validation of an Intelligent Prognostic Prediction Platform for Postoperative Outcomes in MESCC Based on Multidimensional Clinical Data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107452
Enrollment
Unknown
Registered
2025-08-12
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal metastases

Interventions

Observational group:None

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 90 years with imaging-confirmed epidural spinal cord compression (ESCC) classified as high-grade or extreme high-grade on the 12-point scale were eligible for inclusion. Participants were required to exhibit at least one of the following progressive clinical manifestations: (A) worsening localized mechanical or radicular pain, (B) deteriorating sensory function, (C) motor impairment in the lower extremities, or (D) sphincter dysfunction. Additionally, candidates had to be surgically eligible with no contraindications and demonstrate willingness to adhere to follow-up protocols.

Exclusion criteria

Exclusion criteria: Patients were excluded if they had primary spinal malignancies (other than spinal myeloma), intramedullary metastases from spinal tumors, or prior surgical/radiotherapeutic intervention at the primary affected vertebral level. Additional exclusions comprised severe comorbidities, including cardiocerebrovascular diseases, respiratory disorders, active severe infections, significant hepatic/renal dysfunction, coagulopathies, or psychiatric conditions that contraindicated general anesthesia or surgery.

Design outcomes

Primary

MeasureTime frame
Postoperative complication;Postoperative muscle loss;Postoperative functional outcome;

Countries

China

Contacts

Public ContactLei Mingxing

Chinese PLA General Hospital

leimingxing2@sina.com+86 188 1177 2189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026