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Vitamin B6 prevents postoperative nausea and vomiting in high-risk patients undergoing lumbar spine surgery: a double-blind randomized controlled study

Vitamin B6 prevents postoperative nausea and vomiting in high-risk patients undergoing lumbar spine surgery: a double-blind randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107441
Enrollment
Unknown
Registered
2025-08-12
Start date
2025-08-13
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

Sponsors

The First Affiliated Hospital of University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age range: 18-65 years old; 2.ASA classification levels 1-3; 3. Patients who plan to undergo elective 1-3 segment posterior lumbar fusion surgery under general anesthesia; 4.PONV high-risk patients.

Exclusion criteria

Exclusion criteria: 1. Allergic to vitamin B6; 2.Long term use of antiemetic drugs or glucocorticoids; 3. Patients who have been taking vitamin B6 for more than three months before surgery; 4. Pregnancy or breastfeeding; 5. Other diseases that may cause nausea and vomiting (such as hepatitis or gastric ulcers); 6. Refuse to participate in the research.

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative nausea and vomiting;

Secondary

MeasureTime frame
The incidence and severity of postoperative nausea or vomiting;Vomiting frequency and antiemetic drug demand;

Countries

China

Contacts

Public ContactYan Wenlong

The First Affiliated Hospital of University of Science and Technology of China

13195456350@163.com+86 551 6228 6350

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026