Facial skin sagging
Conditions
Interventions
Treatment group:Facial facelift treatment
Sponsors
Shenzhen People’s Hospital (The First Affiliated Hospital, Southern University of Science and Technology;The Second Clinical Medical College,Jinan University)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Normal growth and development, with the Body Mass Index (BMI) within 2 standard deviations above or below the median of the same age group; (2) Age ranging from 18 to 60 years old; (3) No systemic diseases or (and) other diseases causing changes in skin thickness; (4) No skin diseases or (and) skin lesions on the head and face; (5) Included in the study for the first treatment, and had not received any other forms of treatment.
Exclusion criteria
Exclusion criteria: (1) Pregnancy period; (2) History of malignant tumors; (3) Individuals with bacterial, viral infections, infectious diseases and compromised immune systems; (4) Those with electronic devices such as pacemakers or automatic defibrillators implanted in their bodies; (5) Individuals with metal implants at the treatment site; (6) Individuals with a history of mental disorders and unable to cooperate with treatment; (7) Other general conditions unsuitable for participating in the study: Participated in any clinical trial within 3 months before screening; Unable to tolerate pain; Had a history of drug abuse or used drugs within 6 months before screening or within 3 months before screening; Had infectious diseases such as syphilis, AIDS, hepatitis B, etc. before screening; Pregnant or lactating subjects; Subjects with a history of serious cardiovascular, gastrointestinal, respiratory, endocrine, kidney, liver diseases, or liver dysfunction, or a history of malignant tumors (diagnosed as malignant tumors within the past 5 years) or central nervous system disorders and unable to fully understand and cooperate with the treatment as per the researcher's opinion; Other combined diseases that the researcher considers may interfere with the study assessment, or the researcher considers that participating in this study may pose greater risks for the subjects; Subjects considered unsuitable for participating in this study by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultra-high frequency ultrasound measurement of the thickness of the dermis and fascia layers of the facial skin;Viscoelastic and elastic technology (for measuring inflammation and collagen hyperplasia around the facial skin);The determination of blood oxygen content in facial skin using photoacoustic ultrasound technology; | — |
Secondary
| Measure | Time frame |
|---|---|
| The VISIA spectrometer and 3D digital shaping scanner were used to evaluate the red areas of the skin, skin moisture and elasticity.;Use dermoscopy to examine the blood vessels of the treated area of the skin;GAIS scoring grade; | — |
Countries
China
Contacts
Public ContactJianglin Zhang
Shenzhen People’s Hospital (The First Affiliated Hospital, Southern University of Science and Technology;The Second Clinical Medical College,Jinan University)
Outcome results
None listed