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A single-blind controlled study of the analgesic nociception index's effect on remifentanil dose and postoperative pain in knee arthroplasty.

A single-blind controlled study of the analgesic nociception index's effect on remifentanil dose and postoperative pain in knee arthroplasty.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107430
Enrollment
Unknown
Registered
2025-08-11
Start date
2024-09-25
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative pain treatment

Interventions

R:Monitoring of NOL with Maygreen Bispro was used to modulate the infusion of the dose used in remifentani
M:Monitoring of NOL with Maygreen Bispro was used to modulate the infusion of the dose used in remifentani

Sponsors

Second Xiangya Hospital of CSU
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.From September 1, 2024 to November 1, 2024, 84 patients undergoing total knee arthroplasty at Xiangya Second Hospital were included in the study. 2.Age>=18 years old; 3.ASA I~II; 4.BMI 18~27.9 kg/m^2;

Exclusion criteria

Exclusion criteria: 1.Minors (< 18 years old); 2.Patients who have been using opioid analgesics, ß-blockers, anticonvulsants or antiepileptic drugs for a long time; 3.patients who are allergic to the test drug; 4.Patients with frontal facial skin damage or inability to undergo EEG monitoring for other reasons; 5.emergency surgery; 6.Those who are unable to cooperate with the completion of VAS score measurement;

Design outcomes

Primary

MeasureTime frame
incidence of VAS scores >= 5;

Secondary

MeasureTime frame
Continuous doses of remifentanil and propofol;VAS score;Probability of nausea and vomiting in the patient;Total length of hospital stay;Quality of Recovery-15;

Countries

China

Contacts

Public ContactDonglin Yang

Second Xiangya Hospital of CSU

yangdl@csu.edu.cn+86 13873156470

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026