Pain after knee arthroplasty
Conditions
Interventions
Experimental group (Group C):The formula is bupivacaine liposome 266mg (20ml)+0.9% physiological saline (10ml), forming a 30ml mixture. Ultrasound guided adductor block is performed before anesthesia.
Control group (group D):The control group was given 30ml of 0.33% ropivacaine solution and underwent ultrasound-guided myotube block before anesthesia.
Sponsors
Puyang People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Aged 18-80 years, with ASA classification of I-III, BMI of 18-28kg/m^2, planning to undergo elective unilateral total knee arthroplasty for the first time, with no history of chronic opioid use (using opioids daily or almost daily for more than 3 months) before surgery
Exclusion criteria
Exclusion criteria: Refusal to participate in this study; history of previous neurological diseases; severe preoperative heart, lung, liver, kidney, and immune function diseases; preoperative schizophrenia, epilepsy, Parkinson's disease, and myasthenia gravis; preoperative inability to communicate due to coma, severe dementia, or language barrier; severe liver dysfunction (Child-Pugh C grade), renal dysfunction (undergoing dialysis before surgery), or expected survival of <= 24 hours; allergy to local anesthetic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The results of the 10 meter walk experiment 24 hours after the injection of the experimental drug; | — |
Secondary
| Measure | Time frame |
|---|---|
| The results of the 10 meter walking experiment at 48h and 72h after the injection of the experimental drug;Record the NRS scores of patients' pain during static and dynamic periods at 24h, 48h, and 72h after the injection of the experimental drug; | — |
Countries
China
Contacts
Public ContactCunli Cao
Puyang People's Hospital
Outcome results
None listed