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Correlation of serum biomarkers with the occurrence of postherpetic neuralgia: a prospective nested case-control study

Correlation of serum biomarkers with the occurrence of postherpetic neuralgia: a prospective nested case-control study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107419
Enrollment
Unknown
Registered
2025-08-11
Start date
2025-08-12
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post herpetic neuralgia

Interventions

Case group (PHN patients) and control group (non PHN patients):None

Sponsors

Nanjing First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients in the acute phase of herpes zoster, within 30 days of disease duration; 2.The patient is proposed to receive a combination of treatments including medications, injection therapy, radiofrequency and electrical stimulation therapy; 3.Over 50 years of age; 4.Consent to participate in this clinical study. Willing to provide blood specimens;

Exclusion criteria

Exclusion criteria: 1.Contraindications to minimally invasive interventional therapy, such as infection, coagulation, etc., that preclude acceptance of HZ's conventional treatment regimens; 2.Presence of central nervous system disease; 3.Presence of severe immunosuppressive diseases such as leukemia, lymphoma, etc; 4.Patients on long-term glucocorticoid therapy or immunosuppressive therapy; 5.Received intrathecal drug injection within 3 months; 6.Pregnant women; 7.Unable to cooperate properly in completing questionnaires and follow-up visits;

Design outcomes

Primary

MeasureTime frame
Pain Numeric Simulation Scoring;

Countries

China

Contacts

Public ContactXu Chenjie

Nanjing First Hospital

xcj2001@126.com+86 25 52271000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026