HER2-positive advanced solid tumors
Conditions
Interventions
HER2-positive advanced solid tumors (non-breast) cohort:None
Sponsors
Shanghai Geriatric Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years; 2.Pathologically confirmed HER2-positive (IHC 3+ or FISH+) solid tumors; 3.Unresectable locally advanced, recurrent or metastatic solid tumors; 4.Patients with complete baseline data (having liver/kidney function tests, ECG, complete blood count, and urinalysis before first antitumor therapy, or clear historical records); 5.Complete follow-up data available (toxicity records or corresponding test results for each treatment cycle, including mandatory liver/kidney function and complete blood count).
Exclusion criteria
Exclusion criteria: 1.Pathologically confirmed breast cancer patients; 2.Patients with severe concurrent infections; 3.Legally incompetent persons, or cases where medical/ethical reasons would affect study continuation; 4.Concurrent participation in other clinical trials; 5.Other conditions deemed unsuitable for inclusion by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective Response Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease Control Rate;Adverse Event;Overall Survival;Progression-Free Survival; | — |
Countries
China
Contacts
Public ContactQian Li
Shanghai Geriatric Medical Center
Outcome results
None listed