Critically Ill Patients
Conditions
Interventions
Gold Standard:In this study, invasive PiCCO transpulmonary thermodilution (TD-CO) measurement is used as the gold standard to evaluate the accuracy of the non-handheld carotid Doppler ultrasound (CDU)
Index test:The diagnostic test (index test) to be evaluated in this study is the non-handheld carotid Doppler ultrasound (CDU) system. This device obtains carotid blood flow velocity and volume parame
Sponsors
Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Age >= 18 years (no gender restriction). (2) Patients: Those admitted to the Intensive Care Unit (ICU) with hemodynamic instability, requiring fluid resuscitation or the use of vasoactive drugs. (3) Vascular Access: Presence of a radial artery or femoral artery catheter to enable invasive hemodynamic monitoring via PiCCO (Pulse Index Continuous Cardiac Output). (4) Informed Consent: Written informed consent obtained from the patient or their family members, with relevant documents signed.
Exclusion criteria
Exclusion criteria: (1) Severe peripheral vascular disease, anatomical structural changes, or local skin and soft tissue infection at the puncture site; severe coagulation dysfunction. (2) Relative contraindications include heparin allergy, local infection at the puncture site; patients receiving intra-aortic balloon pump therapy, hemorrhagic diseases; aortic aneurysm, Takayasu arteritis; arterial stenosis, history of limb embolism; lobectomy, pulmonary embolism, large intrathoracic space-occupying lesions; during cardiopulmonary bypass; excessive short-term fluctuations in body temperature or blood pressure; severe arrhythmias; severe pneumothorax, cardiopulmonary compressive disorders; intracardiac tumors; intracardiac shunts, etc. (3) Infection, dermatitis, cellulitis, burns, trauma, or other conditions in the puncture site or adjacent tissues. (4) Presence of venous injury, embolism at the proximal end of the vein where the catheter is to be placed, or potential arteriovenous fistula. (5) The ipsilateral upper limb of patients who have undergone radical mastectomy, cardiac pacemaker implantation, or axillary lymph node dissection. (6) Superior vena cava syndrome; inability to cooperate or restlessness. (7) Neck wounds that prevent the application of adhesive patches.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Continuous cardiac output;Sensitivity;Specificity;receiver operating curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Physiological parameters of carotid blood flow; | — |
Countries
China
Contacts
Public ContactQuanhong Zhou
Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed