hemorrhagic shock
Conditions
Interventions
group of 1:1:1 component transfusion:1:1:1 component transfusion
group of ABO- and Rh-compatible whole blood:ABO- and Rh-compatible whole blood
low-titer O-group whole blood,LTOWB:low-titer O whole blood
Sponsors
the First Affiliated Hospital of Air Force Medical University (Xijing Hospital)
Eligibility
Sex/Gender
All
Age
10 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) patients with hemorrhagic shock caused by trauma or upper gastrointestinal bleeding who meet the indications for urgent blood transfusion (Hb<7g/dL or active bleeding); (2) age between 10 and 90 years old; (3) The period from onset to hospitalization is less than 24 hours.
Exclusion criteria
Exclusion criteria: (1) severe underlying diseases (end-stage organ failure, malignant tumor); (2) patients with previous coagulopathy or severe transfusion reaction; (3) refusal to participate in the study or inability to follow up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| survival rate (24h,30d);mean arterial pressure;total hospitalization costs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood-product preparation time;total emergency transfusion volume;Length of stay in the emergency resuscitation bay;ICU treatment duration;transfusion-related costs; | — |
Countries
China
Contacts
Public ContactLi Junjie
the First Affiliated Hospital of Air Force Medical University (Xijing Hospital)
Outcome results
None listed