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The effect of acetaminophen mannitol injection for preemptive analgesia on postoperative pain and accelerated recovery after cesarean section

The effect of acetaminophen mannitol injection for preemptive analgesia on postoperative pain and accelerated recovery after cesarean section

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107382
Enrollment
Unknown
Registered
2025-08-11
Start date
2025-08-15
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Interventions

Group A:Intravenous infusion of physiological saline before surgery, postoperative analgesia using 50 micrograms of sufentanil
Group B:Intravenous infusion of acetaminophen before the end of surgery, postoperative analgesia using 50 micrograms of sufentanil
Group C:Intravenous infusion of physiological saline before surgery, postoperative analgesia using 100 micrograms of sufentanil

Sponsors

Linyi Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) Class I-II, aged 18-50 years, gestational weeks 37-41 weeks, body mass index (BMI) 20-35 kg/m^2, selected pregnant women undergoing cesarean section under spinal anesthesia.

Exclusion criteria

Exclusion criteria: Previous cesarean section >= 3 times, BMI>40 kg/m^2, Severe heart, lung, liver, kidney and other important organ lesions, contraindications to spinal anesthesia, mental illness or cognitive impairment, allergies or contraindications to the drugs used in this study, and refusal to participate in the study.

Design outcomes

Primary

MeasureTime frame
VAS scores;Postoperative pain relief situation;

Secondary

MeasureTime frame
Intraoperative vital signs;Postoperative rehabilitation indicators;Incidence of postoperative adverse reactions;

Countries

China

Contacts

Public ContactWang Yuanyuan

Linyi Maternal and Child Health Hospital

377109436@qq.com+86 158 6539 7336

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026