Cognitive impairment
Conditions
Interventions
Observation group:None
Sponsors
Guangdong Second Provincial General Hospital (Guangdong Provincial Emergency Hospital)
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) age 50 or above; 2) voluntary participation or willingness of a guardian to participate in the study, with the signing of informed consent.
Exclusion criteria
Exclusion criteria: 1)a history of dementia of a known non-AD cause; 2)history of severe psychological or psychiatric disorders such as severe anxiety, depression, or schizophrenia, with evident cognitive abnormalities; 3)history of systemic diseases severely affecting the ability to live independently; 4)long-term use of psychotropic drugs; 5)history of traumatic brain injury with sequelae; 6) refusal or inability to cooperate in cognitive function tests; 7) incomplete clinical data; 8) related diseases such as nasal polyps, deviated nasal septum, nasal tumors, or nasal trauma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive status;Olfactory testing;Serum protein biomarker concentrations (Aß???? and p-tau-181); | — |
Countries
China
Contacts
Public ContactPing Luan
Guangdong Second Provincial General Hospital (Guangdong Provincial Emergency Hospital)
Outcome results
None listed