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Study on the efficacy of combined water separation and needle-knife release versus simple water separation release in the treatment of carpal tunnel syndrome

Study on the efficacy of combined water separation and needle-knife release versus simple water separation release in the treatment of carpal tunnel syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107333
Enrollment
Unknown
Registered
2025-08-08
Start date
2025-07-08
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome

Interventions

Water separation combined with needle-knife release group:a needle knife was utilized to transect half of the deep TCL layer
hydrodissection group:Perform a 360° separation of the median nerve between the flexor retinaculum and the transverse carpal ligament, between the transverse carpal ligament and the median nerve, and

Sponsors

Beijing Chao-Yang Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adults aged 18 to 80 years with CTS diagnosed by: (1) numbness, pain, or sensory loss in the median nerve distribution; (2) nocturnal symptom worsening or awakening; (3) thenar atrophy; (4) positive Phalen, Tinel, or compression test; and (5) median nerve injury confirmed by electromyography. Symptoms must persist >= 3 months.

Exclusion criteria

Exclusion criteria: (1) Prior CTS surgery or injection; (2) Coexisting brachial plexopathy or thoracic outlet syndrome; (3) Severe comorbidities (e.g., diabetes, rheumatoid arthritis); or wrist infection.

Design outcomes

Primary

MeasureTime frame
Flattening Ratio (FR);Cross-sectional Area (CSA);Median Nerve Mobility;The Boston Carpal Tunnel Syndrome Questionnaire Symptom Severity Scale (BCTQ-SSS);The Boston Carpal Tunnel Syndrome Questionnaire Functional Status Scale (BCTQ-FSS);Visual Analog Scale (VAS);

Countries

China

Contacts

Public ContactCao Wen

Beijing Chao-Yang Hospital, Capital Medical University

caowenemail@126.com+86 10 8253 1030

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026