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Development and validation of a nomogram (NO-PNALD) for predicting extrapulmonary nutrition-associated liver injury in patients: A retrospective and prospective mixed cohort study based on patients undergoing hematopoietic stem cell transplantation

Development and validation of a nomogram (NO-PNALD) for predicting extrapulmonary nutrition-associated liver injury in patients: A retrospective and prospective mixed cohort study based on patients undergoing hematopoietic stem cell transplantation

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107330
Enrollment
Unknown
Registered
2025-08-08
Start date
2025-08-08
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hematological system diseases

Interventions

The PNALD positive group:None
PNALD negative group:None

Sponsors

The Second Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1 Undergo hematopoietic stem cell transplantation; 2 Receive parenteral nutrition support treatment

Exclusion criteria

Exclusion criteria: 1 Under 18 years old; 2 Those with abnormal liver function before parenteral nutrition treatment; 3 Parenteral nutrition support for less than 5 days; 4 Deceased patients; 5 Incomplete data records

Design outcomes

Primary

MeasureTime frame
glutamic oxalacetic transaminase;glutamic-pyruvic transaminase;total bilirubin;direct bilirubin;—

Countries

China

Contacts

Public ContactMiao Li

The Second Affiliated Hospital of Dalian Medical University

limiaodyey@163.com+86 177 0987 6015

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026