Cardiovascular
Conditions
Interventions
No endoscopy group:None. No gastrointestinal endoscopy guidance/involvement
Endoscopy group:None. Gastrointestinal endoscopy guidance/involvement
Sponsors
The Eighth Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged >>= 18 years who required hospitalization for a gastrointestinal bleeding event; Gastrointestinal bleeding was defined as bleeding in the stomach, duodenum, small intestine, colon, etc., with symptoms of overt gastrointestinal bleeding (vomiting blood, black stool, blood in stool, etc.) and bleeding confirmed by gastroenteroscopy. (e.g., vomiting blood, black stool, blood in stool, etc.) and gastroenteroscopically confirmed bleeding from the stomach, duodenum, small intestine and colon. Or non-obvious gastrointestinal bleeding with hemoglobin lowering more than 2g/L, or accompanied by typical symptoms of peptic ulcer for 3 days. Gastrointestinal ulcer symptoms lasting for more than 3 days with multiple foci of erosion confirmed by gastroenteroscopy, or Gastric perforation, obstruction and other diagnostic imaging evidence. (2) Currently undergoing treatment for cardiovascular, cerebrovascular, pulmonary embolism, peripheral vascular stenosis or occlusion, or other thrombotic diseases. (2) Patients who are currently receiving antiplatelet drugs for previous or recent cardiovascular, pulmonary embolism, peripheral vascular stenosis or occlusion, including thromboxane A2 (TXA2) synthesis inhibitors, ADP receptor antagonists, and phosphodiesterase (PDE) inhibitors alone or in combination. (3) To obtain informed consent from the patients to be followed up. (3) Obtain informed consent from the patients to be followed. Translated with DeepL.com (free version)
Exclusion criteria
Exclusion criteria: (1) Except for gastrointestinal bleeding due to the following causes, such as portal static of various origins Gastrointestinal varices after pulse hypertension, esophageal foreign bodies, Crohn's disease, ulcerative colitis, Intestinal tuberculosis, ischemic bowel disease, inflammatory bowel disease, Meckel's diverticulum, intussusception, Hemorrhoids, anal tears and other causes of gastrointestinal bleeding; (2) Blood system diseases (including abnormal coagulation function); (3) Combined digestive tract tumors; (4) Pregnant or gestational women; (5) Incomplete clinical and follow-up information, or refusal to sign the informed consent or withdraw from the study Patients. Translated with DeepL.com (free version)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rebleeding event;Major cardiovascular and cerebrovascular adverse events;All-cause mortality events; | — |
Countries
China
Contacts
Public ContactHuang Rongchong
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed