Pancreatic cancer
Conditions
Interventions
Case series:None
Sponsors
Beijing Chaoyang Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 80 years; 2. Expected survival of more than 6 months; 3. Undergoing radical resection for pancreatic space-occupying lesions at our center, combined with resection of involved vessels and allogeneic vein grafting; 4. Postoperative pathological confirmation of pancreatic malignancy; 5. No perioperative mortality; 6. Informed consent to participate in the study obtained from the patient.
Exclusion criteria
Exclusion criteria: 1. Patients with a documented history of coagulopathy or active bleeding disorders; 2. Known hypersensitivity or allergic reaction to rivaroxaban or similar agents; 3. History of long-term use of other anticoagulant medications; 4. Presence of preoperative portal venous system thrombosis; 5. Pregnant or breastfeeding women; 6. Severe hepatic or renal dysfunction (hepatic function classified as Child-Pugh class C, or renal insufficiency with eGFR <30 ml/min); 7. Presence of other malignancies or severe systemic diseases; 8. Any other condition deemed unsuitable for study participation by the investigators; 9. Withdrawal from the study for any reason during the observation period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of venous thrombosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bleeding events;Adverse drug reactions;Overall survival;Disease-free survival;Vascular graft patency; | — |
Countries
China
Contacts
Public ContactLang Ren
Beijing Chaoyang Hospital, Capital MedicalUniversity
Outcome results
None listed