Pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 65 years,both sexes; 2. BMI between 18 and 24 kg/m2; 3. Patients scheduled to undergo CT-guided percutaneous localization of pulmonary nodules, followed by video-assisted thoracoscopic surgery; 4. Agree to participate in the study voluntarily, and sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with systemic or puncture-site infections; 2.Patients with known allergy to local anesthetics or contraindications; 3.Patients with significant coagulopathy or hematologic disorders; 4.Patients with severe organ dysfunction (Cardiac: NYHA class III-IV heart failure; Pulmonary: FEV1 < 50% predicted; Hepatic: Child-Pugh grade B/C; Renal: eGFR < 30 mL/min/1.73m²); 5.Patients who are pregnant or lactating; 6.Patients with peripheral neuropathy, pre-existing neurological deficits in the SAPB target area, or anatomically unsuitable for nerve block; 7.Patients unable to communicate or cooperate with study procedures; 8.Patients with other conditions deemed inappropriate by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local anesthetic absorption rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatomal sensory blockade mapping ;Resting/movement-evoked VAS scores;Total intravenous analgesic consumption and rescue analgesia events;The adverse events ;Assessment of the duration of the block effect; | — |
Countries
China
Contacts
The First Affiliated Hospital of the University of Science and Technology of China(Anhui Provincial Hospital)