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CT imaging of ropivacaine diffusion and absorption patterns following serratus anterior plane block

CT imaging of ropivacaine diffusion and absorption patterns following serratus anterior plane block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107321
Enrollment
Unknown
Registered
2025-08-08
Start date
2025-08-15
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

Experimental group:Serratus anterior plane block

Sponsors

The First Affiliated Hospital of the University of Science and Technology of China(Anhui Provincial Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 65 years,both sexes; 2. BMI between 18 and 24 kg/m2; 3. Patients scheduled to undergo CT-guided percutaneous localization of pulmonary nodules, followed by video-assisted thoracoscopic surgery; 4. Agree to participate in the study voluntarily, and sign the written informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with systemic or puncture-site infections; 2.Patients with known allergy to local anesthetics or contraindications; 3.Patients with significant coagulopathy or hematologic disorders; 4.Patients with severe organ dysfunction (Cardiac: NYHA class III-IV heart failure; Pulmonary: FEV1 < 50% predicted; Hepatic: Child-Pugh grade B/C; Renal: eGFR < 30 mL/min/1.73m²); 5.Patients who are pregnant or lactating; 6.Patients with peripheral neuropathy, pre-existing neurological deficits in the SAPB target area, or anatomically unsuitable for nerve block; 7.Patients unable to communicate or cooperate with study procedures; 8.Patients with other conditions deemed inappropriate by investigators.

Design outcomes

Primary

MeasureTime frame
Local anesthetic absorption rate;

Secondary

MeasureTime frame
Dermatomal sensory blockade mapping ;Resting/movement-evoked VAS scores;Total intravenous analgesic consumption and rescue analgesia events;The adverse events ;Assessment of the duration of the block effect;

Countries

China

Contacts

Public ContactYang Jia

The First Affiliated Hospital of the University of Science and Technology of China(Anhui Provincial Hospital)

yangjiahao79@163.com+86 139 6505 9649

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026