Caf-au-lait maeules
Conditions
Interventions
treatment group:The treatment side will receive Q755nm laser first, and then Q1064nm laser treatment if the patient recurs. The control side pigmentation was directly treated with the Q1064nm laser
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients, 1-60 years old (including 1 and 60 years old), regardless of gender; 2. Patients who have received Q755/Q694/Q532nm laser treatment for 5 or more times before and have improved the area of skin lesions by less than 25%; The area of the skin lesion is not less than 2cm^2; 3. All patients undergo dermatoscopy to rule out other pigmented diseases, and patients with a clear diagnosis of coffee milk spots need to undergo skin biopsy if the dermatoscopy cannot confirm the diagnosis. 4. After fully understanding the treatment plan and risks, I voluntarily sign the informed consent form, and am willing to accept my own controlled trial, and cooperate with follow-up and skin biopsy.
Exclusion criteria
Exclusion criteria: 1. Pregnant women or women with pregnancy planning to prepare for pregnancy; 2. Allergic to surface disinfectants; 3. Patients with wounds on the face or epidermal rupture; 4. Patients with severe organic diseases or mental illnesses; 5. Patients who are participating in other clinical trials; 6. Subjects who have undergone laser or energy therapy, aesthetic surgery (e.g., fillers, injections, plastic surgery), and/or chemical ablative treatments in the past 1 year; 7. Subjects with a history of skin healing disorders or scarring; 8. Patients who have participated in or are participating in other drug or device clinical trials within 3 months; 9. Patients with other conditions that the investigator believes are not suitable for participation in this clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective Visual Assessment Score (VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| side effects;patient satisfaction; | — |
Countries
China
Contacts
Public Contactzhen zhang
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed