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Study on the effect of nasal high-flow humidifying oxygen therapy on the prevention of hypoxemia during deep sedation extubation after laparoscopic surgery

Study on the effect of nasal high-flow humidifying oxygen therapy on the prevention of hypoxemia during deep sedation extubation after laparoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107249
Enrollment
Unknown
Registered
2025-08-07
Start date
2025-08-10
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia

Interventions

Experimental group:HFNC oxygen was used after endotracheal extubation under deep sedation
Control group:After endotracheal extubation under deep sedation, oxygen is inhaled using a normal nasal cannula

Sponsors

Bozhou People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age 18-75 years old; 2. Patients with elective laparoscopic surgery under general anesthesia; 3. American Society of Anesthesiologists (ASA) grade I-III; 4. Those who voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Body Mass Index (BMI) > 30kg/m^2; 2. Those with severe heart, lung, liver and kidney dysfunction; 3. High-risk patients with known or expected difficult airway, previous airway surgery or periairway surgery (including thyroid surgery), unable to communicate; 4. Previous gastrointestinal surgery and intestinal obstruction; 5. Those who have used deep sedation or neuromuscular blockers within 48 hours before surgery; 6. Those who have taken drugs that affect gastrointestinal motility within 1 month before the study; 7. Severe water and sodium retention and infection; 8. Those with coagulation dysfunction; 9. Patients admitted to the ICU with a tube after surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of hypoxemia during recovery after extubation;

Secondary

MeasureTime frame
Blood gas analysis index;Hemodynamic indicators and events;Complications during the recovery period after extubation;Management of hypoxemia during the recovery period after extubation;PACU dwell time;Hospitalization days;

Countries

China

Contacts

Public ContactWang Yikai

Bozhou People's Hospital

wangyikai3883@163.com+86 181 5678 3883

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 13, 2026