necrotizing enterocolitis
Conditions
Interventions
control group:Midazolam 2 mg/kg/h and remifentanil 0.25µg kg/min were infused
intervention group:Remifentanil 0.25µg kg/min was infused, and 1%-2% sevoflurane was inhaled continuously during the operation. The minimum alveolar effective concentration (MAC) was maintained at 1.0
Sponsors
Chongqing Health Center for Women and Children
Eligibility
Sex/Gender
All
Age
0.1 Years to 0.3 Years
Inclusion criteria
Inclusion criteria: 1. Stage III NEC; 2. receiving general anesthesia; 3. NEC enterostomy was planned; 4. Admission to NICU after surgery
Exclusion criteria
Exclusion criteria: 1. allergy to narcotic drugs; 2. secondary surgery; 3. preoperative tracheal intubation >=24 hours; 4. It has been included in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory markers in postoperative bronchoalveolar lavage fluid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative plasma inflammatory markers;oxygenation index;static compliance of lung; | — |
Countries
China
Contacts
Public ContactXiaofeng Lei
Chongqing Health Center for Women and Children
Outcome results
None listed