Female infertility
Conditions
Interventions
Conventional IVF group:IVF insemination
ICSI group:ICSI insemination
Sponsors
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Female age = 5×106/mL, PR(grades A+B) >= 10%); 4.Oocyte retrieval number >5; 5.Be capable of giving informed consent.
Exclusion criteria
Exclusion criteria: 1.Documented uterine cavity abnormalities or impaired endometrial receptivity, including but not limited to: Untreated congenital uterine anomalies (septate uterus, unicornuate uterus, didelphys uterus, etc.) Submucosal fibroids Hydrosalpinx (without prior surgical intervention); 2.Women who intend to undergo PGT-SR or PGT-M; 3.Using donor sperm or donor oocytes; 4.Using cryopreserved sperm or cryopreserved oocytes; 5.History of IVF fertilization failure or abnormal fertilization (fertilization rate <= 25%); 6.Semen parameters on oocyte retrieval day not meeting standard IVF criteria (sperm concentration <1×10^6/mL); 7.Contraindications to pregnancy and/or assisted reproductive technologies; 8.Previous participation in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rates of live birth after first embryo transfer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pregnancy loss rate;euploidy rate;Fertilization rate;Cumulative live birth rate;Newborn birth weight;Clinical pregnancy rate;blastocyst rate;Complications during pregnancy and childbirth; | — |
Countries
China
Contacts
Public ContactYun Sun
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed