Recurrent pregnancy loss
Conditions
Interventions
IVF/ICSI group:IVF/ICSI
PGT-A group:PGT-A
Sponsors
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1.women with a history of RPL, RPL refers to a history of >= 2 pregnancy losses before 24 weeks of gestation, among which at least 1 was clinical pregnancy loss; 2. Women under the age of 40 years at the time of informed consent; 3. Women who intend to undergo ART; 4. Women with at least 1 good-quality blastocysts on day 5 or day 6 of embryo culture; 5. Be capable of giving informed consent.
Exclusion criteria
Exclusion criteria: 1. Women with a uterine cavity abnormality, such as a uterine congenital malformation (uterus unicornate, bicornate, or duplex); untreated uterine septum, submucous myoma, multiple endometrial polyp(s); or with untreated hydrosalpinx; 2. Women who are indicated and planned to undergo PGT-M or PGT-SR; 3. Women who use donated oocytes or sperm to achieve pregnancy; 4. Women with medical contraindications to assisted reproductive technology and/or pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live birth rate after initial transfer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neonatal complications, birth weight and birth defects;Ongoing pregnancy rate;Biochemical pregnancy rate;Good birth outcome;Pregnancy loss rate;Complications during pregnancy and childbirth;clinical pregnancy outcome; | — |
Countries
China
Contacts
Public ContactYun Sun
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed