Chronic Insomnia Disorder
Conditions
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS) Group (Group R):Repetitive Transcranial Magnetic Stimulation (rTMS)
Stellate Ganglion Block Group (Group S):Stellate Ganglion Block
Sponsors
RUIJIN-HAINAN HOSPITAL SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE(Hainan Boao Research Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 150 Years
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with chronic insomnia disorder according to the International Classification of Sleep Disorders (3rd edition) by the American Academy of Sleep Medicine (AASM); 2.agree and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.History of any drug abuse, severe neurological or psychiatric illnesses; 2.History of neurosurgical operations or head trauma; 3.pregnancy; 4.People with various electronic medical treatment or auxiliary devices implanted in the body; 5.Individuals wearing or currently using various medical electronic devices or instruments (such as ambulatory electrocardiographs, electronic kidneys, cochlear implants, etc.); 6.Contraindications to magnetic resonance imaging (MRI) or refusal to complete MRI scanning;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index (PSQI); | — |
Secondary
| Measure | Time frame |
|---|---|
| Polysomnography parameters;Sleep diary indicators;Salivary cortisol, serum cortisol, 5-HT (5-hydroxytryptamine), BDNF (brain-derived neurotrophic factor), proBDNF (pro-brain-derived neurotrophic factor), tPA (tissue plasminogen activator), NPS (neuro;Monitoring parameters of sleep monitoring bracelet;Adverse events such as headache, dizziness, and local scalp discomfort;Brain network functional connectivity;Athens Insomnia Scale (AIS);Montreal Cognitive Assessment (MoCA);Hamilton Depression/Anxiety Rating Scale (HAMD/HAMA); | — |
Countries
China
Contacts
Public ContactZhang Liyun
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed