Hip diseases
Conditions
Interventions
Control group:0.375 % ropivacaine 30 ml for FICB,Intravenous injection of saline 10ml.
Intravenous injection group:0.375 % ropivacaine 30 ml for FICB,Intravenous injection of 10ml normal saline containing 0.3mg / kg esketamine.
Adjuvant group:FICB was performed by adding 0.375 % ropivacaine 30 ml of 0.3 mg / kg esketamine for FICB,Intravenous injection of saline 10ml
Sponsors
The 904th Hospital of the Joint Logistic Support Force of PLA
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: The patient is aged 65-80. ASA (American Society of Anesthesiologists) score ranges from I to III; The Body Mass Index (BMI) is between 18 kg/m^2 and 25 kg/m^2. The patient underwent elective unilateral total hip replacement surgery, voluntarily accepted iliac fascia block, and agreed to use postoperative analgesia pump. The clinical data was complete.
Exclusion criteria
Exclusion criteria: coagulation disorders; Infection at the puncture site; Difficult to communicate; Difficulty in cooperation due to mental disorders; Allergic to the anesthetic used in this experiment; Contraindications to esketamine; Multi site surgery; Peripheral nervous system diseases affecting the lower limbs; Refusal to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time of first pressing analgesia pump ( within 48 hours after operation ) ;Within 48 hours after operation, VAS scores for analgesia in rest and movement states and patient satisfaction scores (1means very dissatisfied; 2 means dissatisfied; 3 means basically satisfied; 4 means satisfied; 5 means very satisfied.);The number of pressing times of analgesic pump within 48 hours after operation, the consumption of butorphanol tartrate within 48 hours after operation, and the number of people needing remedial analgesia ;The consumption of propofol and remifentanil during operation ; | — |
Secondary
| Measure | Time frame |
|---|---|
| General information : age, gender, BMI index and operation time;Monitoring the MAP and HR of the three groups of patients at different time points, including admission ( T0 ), 10 min after block ( T1 ), 20 min after block ( T2 ), after induction of anesthesia ( T3 ), skin incision ( T4 ), extubation ( T5 );The onset time and duration time of sensory block after iliac fascia block; QoR-15 score, sleep quality score on the day of operation (1 means good,; 2 means restless,; 3 means nightmare; 4 means insomnia.) and postoperative hospital stay;Complications related to nerve block, such as local anesthetic poisoning and local hematoma. Postoperative adverse reactions such as nausea, vomiting, etc; | — |
Countries
China
Contacts
Public ContactXuandong Jia
The 904th Hospital of the Joint Logistic Support Force of PLA
Outcome results
None listed