Patients treated with CRRT
Conditions
Interventions
Gold Standard:Peripheral blood blood collection to monitor the anticoagulation effect
Index test:Blood sample collection from hemodialysis extracorporeal circulation circuit
Sponsors
Aerospace Center Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age range 18 ~ 80 years old; (2) CRRT patients anticoagulated with nafamostat mesylate; (3) CRRT treatment mode is hemofiltration therapy; (4) Volunteer to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with systemic anticoagulants and severe hematological diseases before CRRT treatment; (2) Combined use of two anticoagulation methods in CRRT treatment; (3) Pregnant or breastfeeding women; (4) Patients requiring additional extracorporeal intervention, including extracorporeal membrane oxygenation or intra-aortic balloon pump, and patients using other anticoagulants (including drugs that can improve anticoagulation levels).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Activated partial thromboplastin time;Accuracy;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of clinically significant bleeding events; | — |
Countries
China
Contacts
Public ContactLi kejia
Aerospace Center Hospital
Outcome results
None listed