Painless Gastrointestinal Endoscopy
Conditions
Interventions
Ciprofol-Etomidate group (C-E group):1ml of ciprofol is approximately equivalent in efficacy to 1ml of propofol. The bolus dose (in ml) is calculated as body weight × 2.5 ÷ 10 (based on the pure propo
Propofol-Etomidate group (P-E group):The bolus dose (in ml) is calculated as body weight × 2.5 ÷ 10 (based on the pure propofol regimen). For the propofol-etomidate group (P-E group), the initial bolu
Sponsors
Wuxi No.2 People's Hospital, Affiliated Central Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Eligibility for sedation confirmed through preliminary preoperative anesthesia evaluation; 2.Age of 18–80 years; 3.ASA (American Society of Anaesthesiologists) grade I–?; 4.Capacity to engage in logical dialogue and address study-related questions pertinently.
Exclusion criteria
Exclusion criteria: 1.New-onset hemodynamic instability; 2.The patient opted against sedation after detailed counseling; 3.Documented psychiatric disorders via medical history review.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic indicators (blood pressure, heart rate, SpO2);CFQ frailty scores when OAA/S score =4; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time from drug administration to loss of eyelash reflex;Total drug administration duration;Presence of severe coughing during gastroscope insertion;Occurrence of intense body movements requiring repeated supplemental doses for suppression; | — |
Countries
China
Contacts
Public ContactZhen Gu
Wuxi No.2 People's Hospital, Affiliated Central Hospital of Jiangnan University
Outcome results
None listed