Granulomatous Mastitis
Conditions
Interventions
Cold Region Group:None. Collection of blood and fecal samples for metabolomic and gut microbiota analysis
Non-Cold Region Group:None. Same as above: collection of blood and fecal samples for analysis
Sponsors
The Sixth Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Female, aged 18–50 years; 2. Diagnosed with granulomatous lobular mastitis (GLM), confirmed by imaging or pathology; 3. Resided in either cold or non-cold regions for at least one year, with place of residence allowing clear group classification; 4. Willing to sign informed consent and complete questionnaires and sample collection; 5. No systemic immunosuppressive therapy (e.g., biologics) in the past year; 6. First-episode or recurrent cases with complete clinical records.
Exclusion criteria
Exclusion criteria: 1. Presence of confirmed malignancies, breast cancer, or Paget’s disease of the breast; 2. Severe psychiatric disorders, cognitive impairment, or communication barriers that prevent study completion; 3. Coexisting systemic autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis); 4. History of extensive breast resection surgery due to prior breast diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in Clinical Characteristics of GLM Patients in Alpine and Non-Alpine Regions; | — |
Countries
China
Contacts
Public ContactLei Zhong
Affiliated with Harbin Medical University
Outcome results
None listed