Postoperative delirium
Conditions
Interventions
Experimental Group:During the surgery, we integrate multiple parameters including the patient state index (PSI), 95% spectral edge frequency (SEF), density spectral arrays (DSA), and burst suppression
control group:During surgery, maintain BIS parameters between 40 and 60.
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of China University of science and technology
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. ASA III level; 2. Age >= 65 years; 3. Elective artificial joint replacement surgery under general anesthesia;
Exclusion criteria
Exclusion criteria: 1. Refusal to participate in this study; 2. Persistent delirium before surgery; 3. Expected to undergo a second surgery within 5 days; 4. Patients undergoing joint revision surgery or multiple joint replacement surgery; 5. Preoperative diagnosis includes the following diseases: Schizophrenia, depression, epilepsy, Parkinson's disease, myasthenia gravis, severe stroke hemiplegia, severe dementia; 6. Illiteracy, language barriers, or severe hearing or visual impairments or other conditions that prevent effective communication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The prevalence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of delirium;Duration of delirium;Time of delirium onset;Postoperative cognitive function score;Postoperative Activities of Daily Living Capacity;Total amount of intravenous and inhalation anesthetics used during surgery, duration of EEG suppression, and duration of hypotension;Total amount of intravenous and inhalation anesthetics used during surgery, duration of EEG suppression, and duration of hypotension;Total amount of intravenous and inhalation anesthetics used during surgery, duration of EEG suppression, and duration of hypotension; | — |
Countries
China
Contacts
Public ContactYingYin
Department of Anesthesiology, the First Affiliated Hospital of China University of science and technology
Outcome results
None listed