Cohort study on central mechanisms underlying chronic low back pain

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500107196

Enrollment

Unknown

Registered

2025-08-06

Start date

2025-08-11

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Low Back Pain

Interventions

Intervention Group:None

Healthy Group:None

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Healthy participants: matched with LBP patients based on age, gender ratio, height, weight, BMI. Lumbago participants: (1)Age 18-75 years old; (2) NRS score>=3; (3) Right-handed (4) Pain or discomfort in the area below the dorsal rib area and above the buttocks.

Exclusion criteria

Exclusion criteria: Healthy participants: have a history of chronic musculoskeletal pain in the past three months. Lumbago participants: (1)Spinal trauma, tumors, infections, surgeries, intraspinal tumors; (2)Recently preparing to become pregnant or pregnant; (3)Those who have severe cognitive and psychological impairments, audio-visual impairments and cannot cooperate with the examination; (4) Kidney disease; (5) Visceral low back pain (such as urolithiasis)

Design outcomes

Primary

Measure	Time frame
The Outcome of Numerical Rating Scale;The Outcome of Roland-Morris Disability Questionnaire;The Outcome of Global Perceived Effect;	—

Secondary

Measure	Time frame
The Outcome of Depression Anxiety and Stress;The Outcome of Cognitive Function;The Outcome of Pain Catastrophizing;Brain Activation;Core Muscle Strength;	—

Countries

China

Contacts

Public ContactHuang Guozhi

Zhu Jiang Hospital of Southern Medical University

zjkfk@smu.edu.cn+86 186 6608 7186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026