Preoperative anxiety
Conditions
Interventions
50µg group:Vital signs of the patients were monitored the night before surgery, and 50µg dexmedetomidine nasal spray was administered for anti-anxiety and sedation without oxygen inhalation.
75µg group:Vital signs of the patients were monitored the night before surgery, and 75µg dexmedetomidine nasal spray was administered for anti-anxiety and sedation without oxygen inhalation.
100µg group:Vital signs of the patients were monitored the night before surgery, and 100µg dexmedetomidine nasal spray was administered for anti-anxiety and sedation without oxygen inhalation.
Sponsors
Wuhan Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Adult patients undergoing elective rectal mucosal resection under spinal anesthesia were less than 60 years old, ASA1-2 grade, Hamilton Anxiety Scale (HAMA) >=7 points, insomnia severity index (ISI) >7 points.
Exclusion criteria
Exclusion criteria: Severe cardiovascular, respiratory system, liver and kidney function, coagulation function abnormalities; Severe sinus bradycardia (heart rate <=50 beats/min) and second degree or more atrioventricular block; Preoperative cognitive dysfunction; Long-term use of sedatives or sleeping pills; Patients judged to have difficulty managing the respiratory tract: modified Markov score level III and above.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ramsay score;total sleep duration; ISI scale score ; preoperative sleep satisfaction score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs at different points in time;Satisfaction score of medical staff with this drug; | — |
Countries
China
Contacts
Public ContactGuangjun Hu
Wuhan Third Hospital
Outcome results
None listed