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Accuracy of Norepinephrine Combined with Mini-Fluid Challenge Test in Predicting Fluid Responsiveness in Hypotensive Patients During General Anesthesia?

Accuracy of Norepinephrine Combined with Mini-Fluid Challenge Test in Predicting Fluid Responsiveness in Hypotensive Patients During General Anesthesia?

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107190
Enrollment
Unknown
Registered
2025-08-06
Start date
2025-08-20
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension?

Interventions

Experimental group:After the patient was admitted to the room, monitoring was established in parallel, and invasive blood pressure monitoring was carried out, and relevant hemodynamic indicators were

Sponsors

Subei People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age 45~75 years old; 2.BMI: 18~30kg/m^2; 3. ASA grade I~III; 4. Patients under general anesthesia who underwent elective gastrointestinal surgery, regardless of gender; 5. Hypotension after invasive pressure monitoring and anesthesia induction (post-induction is defined as the period from induction intubation to before skin incision.) hypotension is defined as systolic blood pressure less than or equal to 90 mmHg or mean arterial pressure decrease of 30% or MAP less than 65 mmHg for one minute during anesthesia); 6. No serious cardiopulmonary and brain function diseases before surgery.

Exclusion criteria

Exclusion criteria: 1. Preoperative hypertension combined with ARB antihypertensive drugs; 2. Preoperative diabetes mellitus; 3. Combined with congenital heart disease and valvular disease; 4. Severe arrhythmia before surgery; 5. Preoperative combined with severe cardiovascular system diseases; 6. Severe respiratory disease before surgery; 7. Severe liver and kidney dysfunction before surgery; 8. The patient explicitly refuses; 9. Persistent hypertension, hypotension or shock during the induction period.

Design outcomes

Primary

MeasureTime frame
heart rate,HR;mean artery pressure, MAP;stroke volume, SV;cardiac index, CI;stroke volume variation, SVV;

Countries

China

Contacts

Public ContactGaoju

Northern Jiangsu People's Hospital,

doctor2227@163.com+86 180 5106 3988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026