Adolescent idiopathic scoliosis
Conditions
Interventions
Low-speed group:Tranexamic acid was infused intravenously at 20-31 drops/min using an infusion pump 6h after surgery in patients with AIS.
Medium speed group:Tranexamic acid was infused intravenously using an infusion pump at 32-43 drops/min for 6h postoperatively in patients with AIS.
normal speed group:Tranexamic acid was infused intravenously at 44-55 drops/min using an infusion pump 6h after surgery in patients with AIS.
Sponsors
West China Tianfu Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
4 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. The patient was diagnosed with adolescent idiopathic scoliosis and underwent PSS; 2. That the patient is >= 4 and <= 18 years of age; 3. The patient does not have any haematological disorders; 4. The patient agrees to participate in this study and signs the relevant informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patient is allergic to TXA; 2. Patient has hepatic and renal insufficiency; 3. Patient has a history of thrombosis; 4. Patient's age 18 years old; 5. Patients with severe cardiovascular and cerebrovascular and other underlying diseases not suitable for surgery; 6. Those with intraoperative dural injuries that produce cerebrospinal fluid leakage; 7. Patients and their families refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nausea;vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electrolyte profile (sodium potassium magnesium calcium chloride);Postoperative blood loss;Hospitalisation satisfaction;Incidence of VTE;Postoperative drainage; | — |
Countries
China
Contacts
Public ContactLiu Li
Sichuan University West China Tianfu Hospital
Outcome results
None listed