postoperative pain
Conditions
Interventions
liposomal bupivacaine group:20ml 266mg liposomal bupivacaine +20ml 0.9% physiological saline
ropivacaine group:10ml 100mg ropivacaine + 30ml 0.9% physiological saline
Sponsors
The Second Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients who plan to undergo thoracoscopic partial lung resection surgery (lung wedge, lung segment, lobe) under general anesthesia, the estimated operation time is >=1 hour; 2. Age>=18 years old; 3. BMI index 18-30kg/?; 4. ASA grade I to II; 5. Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Refusal to participate in this study; 2. Communication disorders, inability to cooperate with researchers, such as language comprehension disorders, mental illness, epilepsy, Parkinson's history or myasthenia gravis, etc.; 3. Those who are allergic to the drugs in this study 4. History of chronic pain such as neuropathic pain before surgery 5. Those who have a history of alcohol, analgesic drugs or other drug abuse and addiction; 6. Those who have participated in other clinical trials within 3 months before being selected for the study; 7. The doctor in charge or the investigator believes that there are other situations that are not suitable for participating in this study (the reason needs to be recorded);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of pain two days after postoperation; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-40(Quality of Recovery-40);postoperative nausea and vomiting incidence;Recovery time (min);postoperative dizziness incidence;the satisfaction scores;postoperative analgesic dosage (mg);patient-controlled analgesia (PCA) demand count;Sufentanil(ug);Propofol (mg);postoperative pulmonary complications incidence; | — |
Countries
China
Contacts
Public ContactChangjun Gao
The Second Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed