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Preliminary study of DCE-MRI multi-parameter analysis of inflammatory activity in axial spondyloarthritis

Preliminary study of DCE-MRI multi-parameter analysis of inflammatory activity in axial spondyloarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500107177
Enrollment
Unknown
Registered
2025-08-05
Start date
2025-08-05
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

axial spondyloarthritis, axSpA

Interventions

Gold Standard:The latest diagnostic criteria of ax-SpA : 1 Low back pain >= 3 months, and the age of onset = 1 features of spondyloarthropathy
or HLA-B27 positive + >= 2 features of spondyloarthropathy. ASAS defined the MRI active signs and structural chang
Index test:According to ASDAS-CRP >= 2.1 as the active group, ASDAS-CRP < 2.1 as the inactive group.

Sponsors

SUN YAT-SEN MEMORIAL HOSPITAL
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ( 1 ) Compliance with the latest diagnostic criteria of ax-SpA ( 2 ) Complete clinical and MRI data.

Exclusion criteria

Exclusion criteria: ( 1 ) Patients with acute and chronic infection, patients with hepatitis B or hepatitis C activity ( 2 ) Patients with malignant tumors ( 3 ) Patients who have previously received tumor necrosis factor ( TNF ) biological agents ( 4 ) Patients with heart, liver and kidney dysfunction who cannot tolerate contrast agent injection ( 5 ) MRI image quality is unqualified.

Design outcomes

Primary

MeasureTime frame
Accuracy;

Secondary

MeasureTime frame
Sensitivity;Specificity;

Countries

China

Contacts

Public ContactZehong Yang

SUN YAT-SEN MEMORIAL HOSPITAL

yangzeh2@mail.sysu.edu.cn+86 20 8133 2199

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026