sarcopenia
Conditions
Interventions
meanwhile, perform low-intensity resistance training 3 times per week.
Sponsors
Capital Medical University
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for sarcopenia AWGS 2019 (i Grip strength less than 28.0 kg for males and less than 18.0 kg for females. ii 6-meter stride speed less than 1.0 m/s or 5-repetition sit-up test time >=12 seconds or SPPB <=9 points. iii BIA less than 7.0 kg/m^2 for males and 5.7 kg/m^2 for females or DXA less than 7.0 kg/m^2 for males and 5.4 kg/m^2 for females); 2. Age between 35-75 years old with high compliance; 3. Complete clinical data; 4. Voluntary participation in the program with informed consent and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1. a clear history of allergy to protein powder in the past 6 months, or the presence of diarrhea symptoms and the frequency of >= 7 days / month, the duration of more than 2 weeks; 2. major physical diseases (diabetes with serious complications, malignant tumors, serious cardiovascular disease, neurological diseases or other diseases that may affect the effectiveness of exercise and nutritional interventions, etc.); 3. the past three months, new fractures and recently underwent joint replacement surgery patients; 4. Suffering from congenital bone or muscle diseases; 5. The simultaneous existence of other comorbidities affecting muscle metabolism, such as malignant tumors, liver disease, severe organ insufficiency such as nephrotic syndrome, renal failure and other diseases that may affect protein metabolism; 6. Participating in other clinical trials patients; 7. With sensory disabilities or other reasons significantly affecting the collection of data, such as severe deafness, blindness, mental disorders, etc.; 8. The researchers The researchers believe that other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physical fitness;Appendicular skeletal muscle mass index;Non handgrip strength;6-minute walk test;Sit-to-stand test;Blood biochemical indices associated with sarcopenia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dietary intake status;General cognitive functioning;Sleep conditions;Daily living skills;Degree of knee injury;Bone mineral density;Knee joint structure and pathology;Serum-associated inflammatory factor;Intestinal flora species;Number of intestinal flora;Level of intestinal flora differentiation;blood lipids;fasting blood glucose;Insulin;Body composition;Height;weight; | — |
Countries
China
Contacts
Public ContactWeiwei Ma
Capital Medical University
Outcome results
None listed