General anesthesia for abdominal surgery
Conditions
Interventions
Remimazolam Tosylate Group:Sedation with remimazolam tosylate
Sponsors
Zigong Fourth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. 18 years old = 3 days. 6. Patients undergoing elective abdominal surgery
Exclusion criteria
Exclusion criteria: 1. Emergency surgery or elective surgery with a duration of = 160 mmHg and/or diastolic blood pressure >= 100 mmHg); 3. abnormal laboratory test results (anemia: Hb = 2.5 × ULN, TBIL >= 1.5 × ULN; abnormal renal function: serum creatinine higher than the upper limit of normal); 4. acute angle-closure glaucoma, myasthenia gravis, acute alcohol intoxication; 5. patients with shock (systolic blood pressure <= 90 mmHg) or coma; 6. patients allergic or resistant to benzodiazepines; 7. pregnant or lactating women; 8. patients requiring cardiopulmonary bypass, hepatectomy or liver transplantation; patients who have participated in other drug clinical trials as 9.subjects within the past 3 months; 10. patients deemed unsuitable for this trial by the researcher, or patients who refuse to participate themselves; 11. patients with contraindications to TEE: known esophageal stricture, obstruction, spasm, diverticulum, dysphagia, large hiatal hernia, tumors or varices/bleeding of the esophagus and stomach, history of esophageal surgery, and intestinal volvulus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular stroke volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac output;Left ventricular shortening fraction;Left ventricular ejection fraction; | — |
Countries
China
Contacts
Public ContactLu Bin
Zigong Fourth People's Hospital
Outcome results
None listed