Septic shock
Conditions
Interventions
CRT normalized targeted resuscitation (CRT-T) group:Fluid resuscitation
Lactate level targeted resuscitation (Lac-T) group:Fluid resuscitation
Sponsors
Wuxi People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The patient met the diagnostic criteria of septic shock 3.0 formulated by the American Society of Critical Care Medicine (SCCM) and the European Society of Critical Care Medicine (ESICM) in 2016. After adequate fluid resuscitation, patients with severe infection still need to use vasoactive drugs to maintain mean arterial pressure (MAP) >=65mmHg (1mmHg = 0.133kPa), accompanied by blood lactic acid (Lac) > 2mmol/L. All patients had to be recruited within 12 hours after the diagnosis of septic shock
Exclusion criteria
Exclusion criteria: 1.Age < 18 years old; 2.Pregnant or lactating women; 3.Raynaud syndrome patient; 4.Patients after cardiopulmonary resuscitation; 5.Patients with severe anemia and methemoglobinemia; 6.Patients with active bleeding; 7.Patients with impaired circulation in the upper extremities,For example, those who have undergone coronary artery bypass grafting (using the radial artery or with preoperative suspicion of radial artery occlusion);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SVRI(Systemic Vascular Resistance Index?);SBRI(snuff-box resistive index);CRT(capillary refill time); | — |
Countries
China
Contacts
Public ContactFengming Liang
Wuxi People's Hospital
Outcome results
None listed