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Evaluation of the clinical effect of potassium nitrate and sodium fluoride in preventing secondary caries on the root surface

Evaluation of the clinical effect of potassium nitrate and sodium fluoride in preventing secondary caries on the root surface

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107136
Enrollment
Unknown
Registered
2025-08-05
Start date
2025-08-12
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Root caries

Interventions

A group:A toothpaste
B group:B toothpaste
C group:C toothpaste

Sponsors

Beijing Stomatological Hospital , Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 30~75 years old, gender is not limited; 2. The diagnostic criteria for root caries adopt the standards recommended by the World Health Organization and the National Institute of Dental Diseases, at least one tooth has gingival recession and exposed caries lesions (including secondary caries) are located on the root surface (when the lesion is located at the enamel dentinal bone boundary, more than 1/2 of the area is located at the root square and is counted as root caries, otherwise it is calculated according to crown caries), the toothbrush can be cleaned, the color is from light yellow to brownish-yellow, soft or astringent, with shallow or deep defects, in line with active root caries; 3. The patient's opening degree is normal and can cooperate with treatment; 4. Have a certain degree of compliance, be able to receive oral hygiene education, and follow the doctor's instructions to brush your teeth.

Exclusion criteria

Exclusion criteria: 1.The looseness of the affected tooth is greater than III.° or should not be retained for other reasons; 2.Cracked teeth; 3.dental caries lesions have caused pulp lesions or periapical lesions; 4.Abnormal occlusion; 5.In the active period of periodontal disease; 6.The total number of natural teeth in the mouth is less than 10; 7.Patients have poor compliance and cannot effectively clean their mouths; 8.Suffering from severe systemic diseases; 9.smokers (> 10 cigarettes/day); 10.Pregnant or lactating women; 11.Have a mental disorder or intellectual disability; 12.Those who are allergic to the three toothpaste ingredients used in the test; 13.Suffering from Sjögren's syndrome.

Design outcomes

Primary

MeasureTime frame
Number of caries on the root surface;Number of dental fillings on the root surface;Pulp vitality test;Electrical impedance measurement of caries on the root surface;Number of caries surfaces on the root surface;Number of caries fillings on the root surface;pH detection of plaque;

Secondary

MeasureTime frame
Hardness and extent of inactive caries;

Countries

China

Contacts

Public ContactLi Shaorong

Beijing Stomatological Hospital Affiliated to Capital Medical University

lsr_professional@163.com+86 10 57088132

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026