Postoperative Hypocalcemia after Thyroidectomy
Conditions
Interventions
Control group:None
Calcium only group:Oral calcium (1800mg/d) was given for 1 days before surgery
Combined group:Oral calcium (1800mg/d) and vitamin D3 (alfacalcalcitol 1ug/d) were given for 1 days before surgery
Sponsors
RuiJin Hospital LuWan Branch, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-60 years; 2.Preoperative diagnosis or high suspicion of thyroid malignancy (TI-RADS =4a) confirmed by ultrasound or fine-needle aspiration; 3.Scheduled for total thyroidectomy with bilateral central lymph node dissection (with or without lateral neck dissection); 4.Willing to provide informed consent and comply with follow-up requirements.
Exclusion criteria
Exclusion criteria: 1.Previous neck surgery; 2.Benign thyroid tumors; 3.Parathyroid disorders; 4.Current use of calcium or vitamin D3 supplements for other medical conditions; 5.Long-term proton pump inhibitor use; 6.Long-term oral contraceptive or estrogen therapy; 7.Severe hepatic or renal insufficiency;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The serum calcium;The serum phosphorus;Serum albumin;Parathyroid hormone;Serum magnesium;Additional intravenous calcium supplementation after surgery;Postoperative hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of tumors;Drainage;Number of lymph nodes;Number of positive lymph nodes;Parathyroid gland lose;Serum 25-hydroxyvitamin D;Maximum tumor diameter; | — |
Countries
China
Contacts
Public ContactJin Xiaoli
RuiJin Hospital LuWan Branch, Shanghai Jiaotong University School of Medicine
Outcome results
None listed