Non-Suicidal Self-Injury (NSSI)
Conditions
Interventions
Healthy control group:None
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: NSSI Group Enrollment Criteria: 1. Adolescents aged 11-18 years who meet the DSM-5 diagnosis of NSSI; 2. Voluntarily participate in the study, and the legal guardian signs a written consent form. Healthy Subjects Group Enrollment Criteria: 1. Adolescents aged 11-18 years old, age, gender, and education level matched to the patient group; 2. Right-handed; 3. Voluntarily participate in the study, and the legal guardian signs a written consent form.
Exclusion criteria
Exclusion criteria: NSSI Group Exclusion Criteria: 1. Consistent with schizoaffective disorder, bipolar disorder, and mental retardation; 2. Psychotic disorders caused by psychoactive substances such as drugs and alcohol; 3. History of brain organic diseases or head injury; 4. Abnormal thyroid function; 5. Endocrine diseases such as diabetes; 6. Severe organ function abnormalities and blood-related diseases; 7. Contraindications to magnetic resonance examination. Healthy subjects group exclusion criteria: 1. History of consciousness disorder for more than five minutes; 2. History of mental illness; 3. Abnormal thyroid function; 4. History of endocrine diseases such as diabetes; 5. Those who have examined blood indicators, heart, liver, and kidney function with serious abnormalities; 6. Contraindications to magnetic resonance examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rest-Functional Magnetic Resonance Imaging;brain activity under the Monetary Incentive Delay task;Risk of suicide;Reinforcement Sensitivity;WHO-5;Parenting style;Sleep quality;Children's Depression Inventory;Ottawa Self-injury Inventory questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Structural Magnetic Resonance Imaging;Brain Myelination Level Measured by Diffusion Magnetic Resonance Imaging;working memory;psychomotor speed;Rumination;Internet Gaming Disorder Scale–Short-Form;brain activity during Go/NoGo task;Quantitative Susceptibility Mapping;Assessment of Peer Victimization;Polygenic risk score;Collectivism-Individualism Tendency Scale;Childhood Traumatic Experience;Assessment of Anhedonia; | — |
Countries
China
Contacts
Public ContactWenwen Shen
Ningbo University Affiliated Kangning Hospital
Outcome results
None listed