Skip to content

Research proposal for laser and drug-assisted treatment of chronic periodontitis

Research proposal for laser and drug-assisted treatment of chronic periodontitis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500107120
Enrollment
Unknown
Registered
2025-08-04
Start date
2020-06-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis

Interventions

Drug-assisted treatment group:Drug-assisted treatment
Laser-assisted treatment group:Laser-assisted treatment

Sponsors

wenzhou peoples hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
36 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Clinically diagnosed with chronic periodontitis; 2.the subjects are of Han ethnicity and permanent residents of Wenzhou; 3.there are at least 20 remaining teeth in the oral cavity, and there is at least one pair of occluding molars in each of the left and right quadrants; 4.non - vegetarians with normal three - meal diets; 5.not pregnant and not lactating; 6.without any systemic, metabolic or oral diseases, especially excluding dental caries, diabetes, digestive diseases, Sjogren's syndrome, hypertension and heart diseases, etc. 7.without smoking or alcohol - drinking behavior; 8.no use of antibiotics and probiotics within the past six months, and no receipt of any form of oral treatment; 9.no intake of antibiotics, steroids, immunosuppressants and probiotics within the past three months.

Exclusion criteria

Exclusion criteria: 1.Patients with poor general conditions are unable to tolerate periodontal basic treatment; 2.there are contraindications to periodontal basic treatment, laser treatment, and drug treatment.

Design outcomes

Primary

MeasureTime frame
microbiome;

Secondary

MeasureTime frame
probing depth;bleeding on probing;clinical attachment loss;

Countries

China

Contacts

Public ContactXiaoqing Li

wenzhou peoples hospital

wzslixq@163.com+86 159 5876 3389

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026